ActiGraft Wound Care System
ActiGraft is an FDA-cleared wound care solution that uses the patient’s own blood to create a blood clot tissue graft. It’s designed to treat chronic wounds such as diabetic foot ulcers, pressure ulcers, venous ulcers, and other hard-to-heal wounds.
How ActiGraft Works
ActiGraft transforms a small sample of the patient’s blood into a solid blood clot tissue that serves as a protective covering for the wound. The process mimics the body’s natural healing process by creating a provisional matrix containing platelets, growth factors, and other components essential for healing.
The procedure involves:
Drawing a small amount of blood from the patient (about 10-15 ml)
Mixing the blood with a coagulant in a specialized kit
Allowing it to clot and solidify (about 10-12 minutes)
Applying the resulting blood clot directly to the wound
Treatment Timeline
Preparation time: The ActiGraft clot can be prepared at the point of care in about 10-12 minutes
Application frequency: Typically applied once weekly
Treatment duration: Varies by wound type and severity, but generally continues until healing is achieved
Dressing changes: The ActiGraft tissue remains on the wound while secondary dressings are changed as needed
Results in Wound Care
ActiGraft has shown significant benefits in wound management:
Promotes wound closure by creating an optimal healing environment
Supplies growth factors and other bioactive substances that stimulate tissue regeneration
Provides a physical barrier that protects the wound from external contamination
Shows effectiveness for wounds that have been unresponsive to standard treatments
Clinical studies report healing rates of 65-75% in previously non-healing wounds
Often reduces healing time compared to standard treatments
May reduce the need for more invasive interventions like skin grafts or amputations
The system is particularly valuable for patients with complex wounds or compromised healing abilities, offering a personalized approach since it uses the patient’s own blood components.